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| Company Name: |
Johnson & Johnson |
| Location: |
Spring House, PA |
| Position Type: |
Full Time |
| Post Date: |
04/29/2026 |
| Expire Date: |
05/29/2026 |
| Job Categories: |
Healthcare, Other, Science, Medical |
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Senior Scientist, Translational Oncology
<p style="text-align:left !important">At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at <a target="_blank" href="https://www.jnj.com."><span style="color:#0000ff"><u>jnj.com</u></span></a>.</p><p></p><p>As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.</p><p></p><p></p><p style="text-align:left"><b><span><span>Job Function: </span></span></b></p>Discovery & Pre-Clinical/Clinical Development<p style="text-align:inherit"></p><p style="text-align:inherit"></p><p style="text-align:left"><b><span><span>Job Sub </span></span><span><span>Function: </span></span></b></p>Translational Discovery & Development Biomarkers<p style="text-align:inherit"></p><p style="text-align:inherit"></p><p style="text-align:left"><b>Job Category:</b></p>Scientific/Technology<p style="text-align:inherit"></p><p style="text-align:inherit"></p><p style="text-align:left"><b>All Job Posting Locations:</b></p>Spring House, Pennsylvania, United States of America<p style="text-align:inherit"></p><p style="text-align:inherit"></p><p style="text-align:left"><b>Job Description:</b></p><p>About Innovative Medicine</p><p>Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.</p><p>Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.</p><p>Learn more at <a href="https://www.jnj.com/innovative-medicine/" target="_blank">https://www.jnj.com/innovative-medicine\</a></p><p></p><p>About Oncology</p><p>Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.</p><p>Our Oncology team is focused on the elimination of cancer by discovering new pathways and modalities to finding treatments and cures. We lead where medicine is going and need innovators with an unwavering commitment to results.</p><p>Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.</p><p></p><p>We are searching for the best talent for a Sr. Scientist, Translational Oncology.</p><p>Purpose: We are seeking a Sr. Scientist Clinical Assay Development to join the Oncology Translational Research (TR) organization in Spring House, PA.</p><p>As a key member of the Clinical Assay Development Group, the successful candidate will lead the design, development, optimization, qualification, and troubleshooting of molecular and protein-based assays in support of oncology clinical programs. The candidate will partner closely with translational scientists, biomarker and diagnostic leads, computational biologists, data management, and clinical operations teams to enable biomarker-driven decision-making across multiple stages of drug development.</p><p>The successful candidate will bring deep hands-on expertise in molecular and immunoassay technologies, a strong understanding of clinical assay development processes, and the ability to operate effectively across multiple programs in a fast-paced, matrixed environment.</p><p>Key Responsibilities</p><ul><li><span>Partner with translational research scientists, biomarker leads, and clinical operations teams to define assay strategies that support exploratory, predictive, and prognostic biomarker endpoints in oncology clinical trials.</span></li><li><span>Design, develop, optimize, and qualify molecular and immunoassay-based clinical assays using technologies such as qPCR, next-generation sequencing (NGS), single-cell analysis platforms, ELISA, and Meso Scale Discovery (MSD).</span></li><li><span>Provide hands-on technical leadership in the execution and troubleshooting of complex analytical workflows, and perform sample analysis in the Spring House laboratories as needed.</span></li><li><span>Support tissue culture and cell-based functional assay activities to complement translational biomarker strategies.</span></li><li><span>Manage and prioritize assay development activities across multiple oncology programs in parallel, ensuring timely delivery of high-quality data to support clinical decision-making.</span></li><li><span>Analyze and interpret complex datasets generated from molecular and immunoassay platforms, and prepare clear, accurate reports and presentations for internal stakeholders and cross-functional teams.</span></li><li><span>Review analytical protocols, reports, and raw data generated by team members to ensure compliance with internal standards and specifications.</span></li><li><span>Maintain rigorous documentation in accordance with Good Laboratory Practices, including sample management, ELN entries, and end-to-end traceability of raw and analyzed data, in line with company SOPs and regulatory requirements.</span></li><li><span>Evaluate and help adopt emerging assay technologies and platforms to strengthen the clinical assay development portfolio.</span></li><li><span>Present research findings and assay development updates at team meetings, departmental seminars, and leadership reviews.</span></li></ul><p>Qualifications</p><p><b>Required</b></p><ul><li><span>Master's degree in Biology, Molecular Biology, Biochemistry, Immunology, or a related life sciences discipline.</span></li><li><span>A minimum of 10 years of relevant experience in the pharmaceutical or biotechnology industry, with a substantial focus on molecular assay development and clinical biomarker support.</span></li><li><span>Extensive hands-on experience with nucleic acid extraction, qPCR, next-generation sequencing (NGS), single-cell analysis technologies, and immunoassay platforms such as ELISA and Meso Scale Discovery (MSD).</span></li><li><span>Demonstrated experience with tissue culture techniques and cell-based assay systems.</span></li><li><span>Strong understanding of clinical assay development processes, including method development, analytical qualification and validation, and transfer to external laboratories.</span></li><li><span>Proven ability to troubleshoot and independently resolve complex assay development challenges.</span></li><li><span>Demonstrated ability to manage multiple projects and competing priorities in a fast-paced, matrixed environment.</span></li><li><span>Excellent written and verbal communication skills, including the ability to clearly present scientific data to diverse audiences.</span></li><li><span>Strong attention to detail and analytical rigor across experimental design, data analysis, and the authoring and review of validation reports.</span></li><li><span>Strong interpersonal skills and a collaborative approach to problem-solving.</span></li></ul><p><b>Preferred</b></p><ul><li><span>Direct experience supporting oncology clinical trials with translational biomarker strategies.</span></li><li><span>Familiarity with regulatory requirements and quality standards applicable to clinical assay development (e.g., CLIA, CAP, GCP).</span></li><li><span>Expertise in additional molecular platforms such as digital PCR, RNA sequencing, or spatial transcriptomics.</span></li><li><span>Experience with complex data analysis using bioinformatics tools.</span></li><li><span>Experience with assay automation and high-throughput workflows.</span></li></ul><p></p><p>Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.<span> </span></p><p></p><p>Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via <a href="https://www.jnj.com/contact-us/careers" target="_blank">https://www.jnj.com/contact-us/careers</a> , internal employees contact AskGS to be directed to your accommodation resource.</p><p></p><p>#LI-Onsite </p><p style="text-align:inherit"></p><p style="text-align:inherit"></p><p> </p><p> </p><p><b>Required Skills: </b></p><p> </p><p> </p><p><b>Preferred Skills:</b></p>Biomarkers, Clinical Trial Designs, Coaching, Communication, Critical Thinking, Drug Discovery Development, Human-Centered Design, Interdisciplinary Work, Medical Compliance, Medical Technology, Quality Standards, Research Documents, Safety-Oriented, Scientific Research, Technologically Savvy, Translational Medicine
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| Company Name: |
Johnson & Johnson |
| Website: | https://jj.wd5.myworkdayjobs.com/en-US/JJ/details/Senior-Scientist--Translational-Oncology_R-071705-1 |
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